Generally I only buy generic, bulk, or Aldi groceries and I find that I don't use coupons for food items very often.
I still love to use coupons though! I like to watch sites such as Money Saving Mom and look for great deals on things I use, like office and medicine cabinet supplies, cleaning things, candles, and fun things like new gadgets or candies.
Because these sites list the coupons and the fliers in which they're found, I don't have cut and sort each coupon every week. I file all the fliers (and All You magazine, which has tons of coupons) into the appropriate month in this document file box that I found on deal for a couple of dollars at Borders.
I originally bought the file box to store magazine clippings, but I've found I like my binders better for that. This is a great system for coupons, because I don't have to deal with them until I want a specific one, and it's pretty quick to find just what I need. I don't have to bother with culling the expired ones until I come back around to that month, and by then I know they're all expired and I can empty the folder right into the recycling.
All in all, this system has saved me a lot of time and energy over my old way of cutting and sorting each coupon.